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Common and clinically significant side effects include gastrointestinal discomfort, nausea, flushing, persistent lymphopenia, and, in rare cases, treatment-associated progressive multifocal leukoencephalopathy (PML) (Naismith et al., 2020

Fisher CL, Cabelli DE, Hallewell RA, et al

However, clinical experience with this drug remains limited

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This increase in absorption suggests that quercetin glucoside facilitates interaction with epithelial glucose transporters, leading to a more rapid uptake and improved bioavailability of glucosides following ingestion ( The biodegradation of larger flavone molecules into more minor, low molecular weight compounds is necessary to cross the intestinal epithelium